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Brugia malayi: status of host during different stages of infection.

Identifieur interne : 00DE83 ( Main/Exploration ); précédent : 00DE82; suivant : 00DE84

Brugia malayi: status of host during different stages of infection.

Auteurs : A. Joshi [Inde] ; J K Saxena ; P K Murthy ; A B Sen ; S. Ghatak

Source :

RBID : pubmed:2527791

Descripteurs français

English descriptors

Abstract

The status of glycogen, protein, lipid components, lipid peroxides and a few enzymes of energy metabolism was studied in liver of Mastomys natalensis during the development of Brugia malayi infection. Glycogen and lipid contents were decreased during the patent phase of infection while total protein was slightly altered in latent animals. Phospholipid and triglyceride contents declined at prepatent and patent phase of infection. The levels of lactate and malate dehydrogenases, as well as of adenosine triphosphatases (Na+K+, Mg2+, Ca2+), were significantly elevated and monoamine oxidase activity was decreased at patent phase of infection, while succinic dehydrogenase remained unaltered. The lipid peroxide formation was enhanced in liver during the development of filarial infection.

PubMed: 2527791


Affiliations:


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Le document en format XML

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<term>Monoamine Oxidase (analysis)</term>
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<div type="abstract" xml:lang="en">The status of glycogen, protein, lipid components, lipid peroxides and a few enzymes of energy metabolism was studied in liver of Mastomys natalensis during the development of Brugia malayi infection. Glycogen and lipid contents were decreased during the patent phase of infection while total protein was slightly altered in latent animals. Phospholipid and triglyceride contents declined at prepatent and patent phase of infection. The levels of lactate and malate dehydrogenases, as well as of adenosine triphosphatases (Na+K+, Mg2+, Ca2+), were significantly elevated and monoamine oxidase activity was decreased at patent phase of infection, while succinic dehydrogenase remained unaltered. The lipid peroxide formation was enhanced in liver during the development of filarial infection.</div>
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